This paper promotes a unique system dynamics-discrete event simulation hybrid modelling framework. The way the hybrid model is developed is intended to simplify the modelling process and make the framework flexible to a variety of situations. In the current study, the framework is used to investigate the success possibility of introducing within-shift job rotation in the plant and its optimal frequency. The intention is to reduce worker exhaustion and by so doing increase productivity and manufacturing throughput. The improvement decisions generated from the simulation results could not have been achieved using any other means. The hybrid modelling framework presents a coherent, straightforward standardized approach that includes the main tasks in SD-DES hybrid modelling. A recommendation for future research is to test the framework’s adaptability to a variety of settings.