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Reflections on Two Approaches to Hybrid Simulation in Healthcare Joe Viana, University of Southampton. Winter Simulation Conference, 2014.

Hybrid simulation, the combination of simulation paradigms to address a problem is becoming more popular as the problems we are presented with become more complex. This is evidenced by an increase in the number of hybrid papers published in specific domains and the number of hybrid simulation frameworks being produced across domains.
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A Modular Simulation Model For Assessing Interventions For Abdominal Aortic Aneurysms Christoph Urach, Günther Zauner, Gottfried Endel, Ingrid Wilbacher, Felix Breitenecker, Proceedings of the 2013 Winter Simulation Conference

This paper discusses the development of an individual based simulation of interventions for better treatment of patients with abdominal aortic aneurysms (AAA). The interdisciplinary subject required collaboration of medical doctors, Health Technology Assessment (HTA) experts and modelers.
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Prospective Healthcare Decision-Making By Combined System Dynamics, Discrete-Event And Agent-Based Simulation Anatoli Djanatliev, Reinhard German, Proceedings of the 2013 Winter Simulation Conference

Prospective Health Technology Assessment allows early decision making for innovative health care technologies. In our recent publications a hybrid simulation approach with System Dynamics and Agent-Based Modeling has been presented. This paper presents a mechanism to generate agents dynamically from SD models and extends the previously presented hybrid approach by process-oriented Discrete Event Simulation for hospital modeling.
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Simulazione discreta con il software AnyLogic. Caratteristiche generali e applicazione ad unostudio oculistico Mattia Munaro, the University of Padua, Faculty of Engineering, 2009-2010

AnyLogic è un ambiente di modellazione virtuale di sistemi discreti, continui ed ibridi. Con questo strumento è possibile creare prototipi di sistemi durante le fasi di studio, progettazione o sviluppo, attraverso cui esplorare aspetti e dettagli della progettazione o della implementazione dei relativi sistemi in modo semplice e privo di rischi
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Toward Simulation-Based Real-Time Decision-Support Systems for Emergency Departments Yariv N. Marmor, Segev Wasserkrug, Avraham Shtub. 2009 Winter Simulation Conference (WSC’09), December 13-16, Austin, TX, USA

Emergency Departments (EDs) require advanced support systems for monitoring and controlling their processes: clinical, operational, and financial. A prerequisite for such a system is comprehensive operational information (e.g. queueing times, busy resources,…), reliably portraying and predicting ED status as it evolves in time. To this end, simulation comes to the rescue, through a two-step procedure that is hereby proposed for supporting real-time ED control.
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A Modern Simulation Approach for Pharmaceutical Portfolio Management Kirk Solo and Mark Paich. International Conference on Health Sciences Simulation (ICHSS'04), January 18 - 21, 2004, San Diego, California, USA

By creating an integrated simulation environment that models the underlying structure of a pharmaceutical enterprise portfolio it becomes possible to identify the optimal longitudinal allocation of finite resources across the constellation of available investment opportunities. The implementation of a hybrid approach that integrates multiple modeling techniques and analytic disciplines allows for a comprehensive environment that captures the underlying dynamics that drive observed market behavior. The implementation of an object oriented model structure constrains the models complexity by supporting dynamic re-use of both structure and logic.
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Decreased length of stay after addition of healthcare provider in emergency department triage Theodore Eugene Day, Abdul Rahim Al-Roubaie, Eric Jonathan Goldlust; EMJ Online First, August 22, 2012

The objective of this paper was to determine the effects of adding a healthcare provider in triage on average length of stay (LOS) and proportion of patients with >6 h LOS. The other goal was to assess the accuracy of computer simulation in predicting the magnitude of such effects on these metrics.
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A multi-paradigm, whole system view of health and social care for age-related macular degeneration Joe Viana, Stuart Rossiter, Andrew A. Channon, Sally C. Brailsford, Andrew Lotery, WSC-2012, Berlin

This paper presents a hybrid simulation model for the management of an eye condition called age-related macular degeneration, which particularly affects the elderly. The model represents not only the detailed clinical progression of disease in an individual, but also the organization of the hospital clinic in which patients with this condition are treated and the wider environment in which these patients live (and their social care needs, if any, are met). The model permits a ‘whole system’ societal view which captures the interactions between the health and social care systems
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